In biology, nothing is clear, everything is too complicated, everything is a mess, and just when you think you understand something, you peel off a layer and find deeper complications beneath. Nature is anything but simple.

~ Richard Preston, The Hot Zone: A Terrifying True Story

Friday 7 September 2012

Homostasis - Circulatory System Part 3 - 28 and 2

Structural Similarities of Arteries and Veins

The walls of both arteries and veins have three similar layers. On the outside, a layer of connective tissue with elastic fiber allows the vessel to stretch and recoil. A middle layer has smooth muscle and more elastic fibers. Lining the lumen of all blood vessels is an endothelium, a single layer of flattened cells that minimizes resistance to blood flow. 

Adaptations of Structure to Functions - Arteries

  • Carry blood away from the heart to the tissues
  • Carry oxygenated blood EXCEPT pulmonary artery
  • Thick muscular walls provide strength to accommodate blood pumped rapidly and at high pressure by the heart and their elasticity (elastic recoil) helps maintain blood pressure even when the heart relaxes.

Adaptations of Structure to Functions - Veins 

  • Carries blood TOWARDS the heart from the tissues 
  • Carry deoxygenated blood EXCEPT pulmonary vein
  • The thinner-walled veins convey blood back to the heart at low velocity and pressure. Blood flows through the veins mainly because skeletal muscle contractions squeeze blood in veins.
  • Have valves to prevent backflow of blood hence blood flow only towards the heart.

 Adaptation of Structure to Functions - Blood Capillaries  

  • Very thin-walled 
  • Very small in diameter
  • The exchange of substances (mainly diffusion) between the blood and interstitial fluid that bathes the cells takes place across the thin endothelial walls of the capillaries.  

Functional Comparison Between Arteries and Veins

 Arteries
  • Transport blood away from the heart
  • Transports blood under higher pressure (than veins)
  • Carry Oxygenated Blood (except in the case of the Pulmonary Artery) 
Veins
  • Transport blood towards the heart
  • Transports blood under lower pressure (than arteries)
  • Carry De-oxygenated Blood (except in the case of the Pulmonary Vein)

Structural Comparision Between Arteries and Veins

Arteries 
  • Have relatively more muscle/elastic tissue 
  • Have relatively narrow lumens
  • Do not have valves (except for the semi-lunar valves of the pulmonary artery and the aorta)
Veins
  • Have relatively less muscle/elastic tissue
  • Have relatively wide lumens
  • Have valves throughout the main veins of the body. These are to prevent blood flowing in the wrong direction, as this could (in theory) return waste materials to the tissues. 


Homostasis - Circulatory System Part 2 - 28 and 29 August 2012


The heart

Has involuntary muscle, 4 chambers (right atria, left atria, right ventricle and left ventricle). 

The ventricles  

The ventricle pumps blood at high pressure out to the arteries (to the lungs or other parts of the body).

The pressure generated by the left ventricle is greater than that generated by the right ventricle as the systemic circuit is more extensive than the pulmonary circuit. 

The atrium 

The atrium receives blood at lower pressure from the veins (coming from the lungs or other parts of the body).

The pressure generated by the atria is lower than that generated by the ventricles since the distance from atria to ventricles is less than that from ventricles to circulatory system.

The valves 

1) Ensure that the blood flows in the correct direction. 
2) Very important; without them, the flow of blood would be chaotic. 
3) Found in the heart and veins.

Tricuspid valve
  • Separates the right atrium from the right ventricle. 
  • It opens to allow the de-oxygenated blood collected in the right atrium to flow into the right ventricle. 
  • It closes as the right ventricle contracts, preventing the blood from returning to the right atrium; thereby forcing it to exit through the pulmonary valve into the pulmonary artery. 
Bicuspid valve / Mitral valve
  • Separates the left atrium from the left ventricle. 
  • It opens to allow the oxygenated blood collected in the left atrium to flow into the left ventricle. 
  • It closes as the left ventricle contracts, thereby forcing it to exit through the aortic valve into the aorta.  
Pulmonary valve 
  • Separates the right ventricle from the pulmonary artery. 
  • As the ventricles contracts, it opens to allow the de-oxygenated blood collected in the right ventricle to flow into the lungs. 
  • It closes as the ventricles relax, preventing blood from returning to the heart.
Aortic valve 
  • Separates the left ventricle from the aorta.
  • As the ventricle contracts, it opens to allow the oxgenated blood collected in the left ventricle to flow throughout the body.
  • It closes as the ventricles relax, preventing blood from returning to the heart. 
Superior and Inferior Vena Cava

Superior Vena Cava is one of the two main veins bringing de-oxygenated blood from the body to the heart. Veins from the head and upper body feed into the Superior Vena Cava, which empties into the righ atrium.

Inferior Vena Cava is the other main vein that brings de-oxygenated blood from the body to the heart. Veins from the legs and the lower torso feed into the Inferior Vena Cava, which empties into the right atrium.

Aorta

Carries oxygenated blood from the left ventricle to the systematic circulation. The aorta is an elastic artery and as such is quite distensible. When the left ventricle contracts to force into the aorta, the aorta expands. This stretching gives the potential energy that will help to maintain blood pressure during diastole, as during this time the aorta contracts passively. 

Pulmonary Artery    

The pulmonary arteries carry blood from the heart to the lungs. They are the only arteries other than the umbilical arteries in the fetus that carry de-oxygenated blood. 

In the human heart, the pulmonary trunk (pulmonary artery or main pulmonary artery) begins at the base of the right ventricle. It is short and wide - about 5cm in length and 3cm in diameter. It then branches into 2 pulmonary arteries (left and right), which deliver de-oxygenated blood to the corresponding lung. 

Pulmonary vein

The 4 pulmonary veins carry oxygenated blood from the lungs to the left atrium of the heart. They are the only veins in the post-fetal human body that carry oxygenated blood. 

Chordae Tendineae

The chordae tendineae, or heart strings, are cord-like tendons that connect the papillary muscles to the tricuspid valve and bicuspid valve. When the right ventricle of the heart contracts, the blood pressure pushes the tricuspid valve which closes and prevents backflow of the blood into the right atrium. The chordae tendineae prevents the flaps from being averted into the right atrium. Similarly, these cord-like tendons hold in position other flaps like the bicuspid valve.

Papillary muscle

In anatomy, the papillary muscles of the heart serve to limit the movement of the mitral and tricuspid valves. These muscles contract to tighten the chodae tendineae, which in turn prevent inversion.

This occurs in respond to pressure gradients. Instead, they brace the valves against the high pressure, preventing regurgitation of ventricular blood back into the atrial cavities. 

Coronary arteries 

The heart is composed primarily of cardiac muscle that continuously contract and relaxes, it must have a constant supply of oxygen and nutrients. 

The coronary arteries are a network of blood vessels that carry oxygen and nutrient rich blood to the cardiac muscle tissues. The larger vessels travel along the surface of the heart. The smaller branches, the cappilaries, penetrate the heart muscle. They are so small that the Red Blood Cells must travel in a single file.  

Homostasis - Circulatory System Part 1 - 28 and 29 August 2012

Mechanism of Nutrition of Amoeba - Ingestion

The food is ingested at the point where it comes in touch with the cell surface with the help of pseudopodia. Pseudopodia engulf the food into the cytoplasm. The process of ingestion takes about 2 minutes.

Mechanism of Nutrition of Amoeba - Digestion and absorptionDigestion - Pseudopodia secretes a sticky and toxic fluid which adheres and kills the prey. It is then taken in by invagination to form a food vacuole whereby chemical digestion takes place.


Absorption - The food is converted into diffusible form and it is readily absorbed by the cytoplasm. The vacuole and becomes progressively smaller as the food is absorbed by diffusion.

 Mechanism of Nutrition of Amoeba - Assimilation and Egestion

Assimilation - These nutrients are used to build new protoplasm and to provide energy for the amoeba.

Egestion - The egestion takes place by exocytosis. There is no particular point from which the egestion takes place. As the amoeba moves forward, the undigested matter is shifted to the back and eliminated as food pellets through a temporary opening formed at any nearest point on the cell membrane. 

Transport in Humans 

Main transport system is called the Circulatory System. 

The Circulatory system works with 
1) the Respiratory system (Exchanges Carbon dioxide and Oxygen)
2) the Digestive system (Carries nutrients and wastes to/from the cells)
3) Works with the Excretory system (Carries waste to kidney for removal)

Human Circulatory System 

Consist of 
1) Cardiovascular System (Made up of Heart, Blood Vessels, Blood)
2) Lymphatic System (Made up of Lymph, Lymph nodes, Lymph vessels)

Cardiovascular System

Consists of 4 components 

1. Blood - The main 'transportation service' that handles the distribution of nutrients, oxugen and hormones to the various regions of the body.

2. Arteries and Veins - A system of tubes that form the transport route where blood flows.

3. Heart - The motor of this transport service.

4. Capillaries - are sites of exchange.

Divided into 

1. Pulmonary System and heart (Pulmonary = lungs)

2. Coronary System (Coronary = heart)

3. Systemic Circulation (Systemic = rest of body)

Double Circulation in Mammals 

Blood passes through the heart twice for each complete circuit of the body. 

Deoxygenated blood flows from the main circulation of the body to the heart, then to the lungs and oxygenated blood returned back to the heart (pulmonary circulation) before it is pumped into the main circulation and circulated to all parts of the body except the lungs (systematic circulation).